The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages The report reviews Midkine (Amphiregulin Associated Protein or Midgestation And Kidney Protein or Neurite Outgrowth Promoting Factor 2 or MDK) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources The report provides a snapshot of the global therapeutic landscape for Midkine (Amphiregulin Associated Protein or Midgestation And Kidney Protein or Neurite Outgrowth Promoting Factor 2 or MDK) Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data. Report covers products from therapy areas Oncology, Genito Urinary System And Sex Hormones, Immunology, Metabolic Disorders, Gastrointestinal, Musculoskeletal Disorders, Cardiovascular and Respiratory which include indications Inflammation, Diabetic Nephropathy, Kidney Fibrosis, Liver Fibrosis, Non-Small Cell Lung Cancer, Acute Renal Failure (ARF) (Acute Kidney Injury), Autoimmune Disorders, Bone Disorders, Bone Fracture, Chronic Kidney Disease (Chronic Renal Failure), Fibrosis, Focal Segmental Glomerulosclerosis (FSGS), Glioblastoma Multiforme (GBM), Glomerulonephritis, Ischemia Reperfusion Injury, Kidney Disease, Lung Disease, Neuroblastoma, Osteoporosis, Osteosarcoma, Prostate Cancer, Solid Tumor and Squamous Non-Small Cell Lung Cancer. Similarly, the universities portfolio in Preclinical stages comprises 2 molecules, respectively. Currently, The molecules developed by companies in Preclinical stages are 6 respectively. It also reviews key players involved in Midkine (Amphiregulin Associated Protein or Midgestation And Kidney Protein or Neurite Outgrowth Promoting Factor 2 or MDK) targeted therapeutics development with respective active and dormant or discontinued projects. The report 'Midkine - Pipeline Review, H1 2018' outlays comprehensive information on the Midkine (Amphiregulin Associated Protein or Midgestation And Kidney Protein or Neurite Outgrowth Promoting Factor 2 or MDK) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type that are being developed by Companies / Universities. It is involved in neointima formation after arterial injury and early fetal adrenal gland development. It binds to anaplastic lymphoma kinase which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate, activation of mitogen-activated protein kinase and PI3-kinase and the induction of cell proliferation. Midkine (Amphiregulin Associated Protein or Midgestation And Kidney Protein or Neurite Outgrowth Promoting Factor 2 or MDK) - Midkine (MDK) or neurite growth-promoting factor 2 is a protein encoded by the MDK gene. Out of which approximately 6 molecules are developed by companies and remaining by the universities/institutes. Midkine (Amphiregulin Associated Protein or Midgestation And Kidney Protein or Neurite Outgrowth Promoting Factor 2 or MDK) - Pipeline Review, H1 2018Īccording to the recently published report 'Midkine - Pipeline Review, H1 2018' Midkine (Amphiregulin Associated Protein or Midgestation And Kidney Protein or Neurite Outgrowth Promoting Factor 2 or MDK) pipeline Target constitutes close to 8 molecules.
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